Cerebellar High-Grade Glioma In A 6-Year-Old Female Child A Literature Review And Case Analysis Rubrique Article

Résumé

Background : Paediatric cerebellar glioblastoma is an exceptionally rare clinical entity, with very few cases described in the literature. These tumors have been reported with an incidence of less than 3% and are associated with poor prognosis despite aggressive treatment.

Case Presentation : We report the case of a 6-year-old female child who presented with balance and gait disturbances for one month. Clinical examination revealed cerebellar ataxia, dysmetria, dysdiadochokinesia, and left hemiparesis. Imaging showed a paramedian solid infratentorial mass lesion in the right cerebellar hemisphere, infiltrating the superior and middle cerebellar peduncles and the brainstem. The patient underwent tumor resection following ventriculoperitoneal shunt placement. Postoperative complications included intracavitary hematoma, cerebellar syndrome aggravation, and right seventh cranial nerve palsy.

Histopathological examination revealed a high-grade (4) diffuse astrocytoma (glioblastoma).

Due to complications, radiotherapy was not administered, and the patient succumbed two months after surgery.

Conclusion : Pediatric cerebellar glioblastomas remain rare but highly aggressive tumors with limited treatment options and poor survival rates. Multimodal therapeutic approaches, including maximal safe resection and adjuvant therapy, are critical to improving patient outcomes. Ongoing research is needed to enhance early detection and therapeutic strategies.